Osteochondral allograft transplantation (OCA) has been demonstrated to be a viable single-stage cartilage restora-tion procedure that restores hyaline cartilage at the artic-ular surface and addresses any underlying subchondral bone injury in patients with focal osteochondral lesions of the knee.8,14,28 The cartilage cells can survive the transplantation only if the tissue is âfreshâ, which means it has not been exposed to radiation or prolonged freezing. Prognostic Factors. 7 noted that patients with an osteochondral allograft due to SONK are likely to have lower satisfaction rates (46%) and poorer outcomes (83%). Such defects often occur in people far too young to have knee arthroplasty, for whom the main alternative to OCA is conservative symptomatic care, which will not prevent development of osteoarthritis. Of the 19 studies, 8 reported prognostic indicators that may affect allograft survival and functional outcomes. Thus, osteochondral allograft (OCA) transplantation represents a 1-step procedure to repair large chondral defects without the donor site morbidity of osteochondral autograft transplantation. Recent studies have reported high success rates with the use of osteochondral allografts. Osteochondral Allograft Transplantation for Osteochondral Defects of the Knee. 2, 7, 8, 11, 16, 17, 20, 22, 26 Bayne et al. Allografting or, to give its full name, âfresh osteochondral allograft transplantation (OCA)â is an operation in which a damaged or diseased area of a joint is reconstructed using a bone and cartilage transplant. Male and female patients â¥40 years of age undergoing OCA were compared to a cohort of patients <40 who had undergone the same surgery. Osteochondral allograft transplantation is emerging as a promising treatment for full-thickness articular cartilage defects. Purpose:To perform asystematic reviewofclinical outcomes andfailure rates after OCA transplantation inthe kneeat aminimum mean 2 yearsâ follow-up. Osteochondral allografts (OCA) consist of a layer of hyaline cartilage and a layer of underlying bone. 4 The authors made no mention of second looks and just noted no resolution of symptoms or abnormal MRI findings. Conclusion: In this series, there was a 37% reoperation rate and an 87% allograft survival rate at a mean of 5 years after OAT. Fresh osteochondral allografts in the knee: comparison of primary transplantation versus transplantation after failure of previous subchondral marrow ⦠BACKGROUND: Osteochondral allograft transplantation (OCA) is often performed with concomitant meniscus allograft transplantation (MAT) as a strategy for knee joint preservation, although to date, the effect of concomitant MAT on outcomes and failure rates after OCA has not been assessed. ... OCA transplantation can be used with success in settings beyond isolated lesions of a femoral condyle. In assessing the use of particulated juvenile cartilage allograft transplantation, Dekker and coworkers in 2018 noted a failure rate of 40 percent in their series of patients with osteochondral lesions of the talus at Duke University. They are used to repair combined defects of articular cartilage and bone. The study compared the results of patients who received osteochondral allograft transplants at MU Health Careâs Missouri Orthopaedic Institute.
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